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Volume 5, Issue 1 (2015), Pages [1] - [78]
SYNTHESIS AND CHARACTERIZATION OF SOME METAL COMPLEXES WITH A LIGAND DERIVED FROM NOVEL 1,2,3-TRIAZOLE DERIVATIVE AND EVALUATION OF THEIR ANTICANCER ACTIVITIES AND THE PERCENT OF uPA INHIBITION IN VITRO
[1] M. Hanif and Z. H. Chohan, Design, spectral characterization and biological studies of transition metal (II) complexes with triazole Schiff bases, Spectrochim Acta A Mol. Biomol. Spectrosc. 104 (2013), 468-476.
[2] N. S. Vatmurge, B. G. Hazra, V. S. Pore, F. Shirazi, P. S. Chavan and M. V. Deshpande, Synthesis and antimicrobial activity of beta-lactam-bile acid conjugates linked via triazole, Bioorg. Med. Chem. Lett. 18 (2008), 2043-2047.
[3] M. Whiting, J. Muldoon, Y. C. Lin, S. M. Silverman, W. Lindstron, A. J. Olson, H. C. Kolb, M. G. Finn, K. B. Sharpless, J. H. Elder and V. V. Fokin, Inhibitors of HIV-1 protease by using in situ click chemistry, Angew. Chem. Int. Ed. 45 (2006), 1435-1439.
[4] V. D. Bock, D. Speijer, H. Hiemstra and J. H. V. Maarseveen, 1,2,3-Triazoles as peptide bond isosteres: Synthesis and biological evaluation of cyclotetrapeptide mimics, Org. Biomol. Chem. 5 (2007), 971-976.
[5] N. G. Aher, V. S. Pore, N. N. Mishra, A. Kumar, P. K. Shukla, A. Sharma and M. K. Bhat, Synthesis and antifungal activity of 1,2,3-triazole containing fluconazole an alogues, Bioorg. Med. Chem. Lett. 19 (2009), 759-763.
[6] J. A. Demaray, J. E. Thuener, M. N. Dawson and S. J. Sucheck, Synthesis of triazoleoxazolidinones via a one-pot reaction and evaluation of their antimicrobial activity, Bioorg. Med. Chem. Lett. 18 (2008), 4868-4871.
[7] D. R. Buckle, D. J. Outred, C. J. M. Rockell, H. Smith and B. A. Spicer, Studies on n-triazoles, 7. antiallergic 9-oxo-1H, 9H-benzopyrano [2,3-d]-n-triazoles, J. Med. Chem. 26 (1983), 251-254.
[8] M. J. Giffin, H. Heaslet, A. Brik, Y. C. Lin, G. Cauvi, C. H. Wong, D. E. McRee, J. H. Elder, C. D. Stout and B. E. Torbett, A copper (I)-catalyzed 1,2,3-triazole azidealkyne click compound is a potent inhibitor of a multidrug-resistant HIV-1 protease variant, J. Med. Chem. 51 (2008), 6263-6270.
[9] S. R. Patpi, L. Pulipati, P. Yogeeswari, D. Sriram, N. Jain, B. Sridhar, R. Murthy, D. T. Anjana, S. V. Kalivendi and S. Kantevar, Design, synthesis, and structure activity correlations of novel dibenzo [b, d] furan, dibenzo [b, d] thiophene, and N-methylcarbazole clubbed 1,2,3-triazoles as potent inhibitors of mycobacterium tuberculosis, J. Med. Chem. 55 (2012), 3911-3922.
[10] R. D. Simone, M. G. Chini, I. Bruno, R. Riccio, D. Mueller, O. Werz and G. Bifulco, Structure-based discovery of inhibitors of microsomal prostaglandin E2 synthase-1,5-lipoxygenase and 5-lipoxygenase-activating protein: Promising hits for the development of new anti-inflammatory agents, J. Med. Chem. 54 (2011), 1565-1575.
[11] Y.-C. Duan, Y.-C. Ma, E. Zhang, X.-J. Shi, M.-M. Wang, X.-W. Ye and H.-M. Liu, Design and synthesis of novel 1,2,3-triazole-dithiocarbamate hybrids as potential anticancer agents, Eur. J. Med. Chem. 62 (2013), 11-19.
[12] L. H. Hurley, DNA and its associated processes as targets for cancer therapy, Nat. Rev. Cancer 2 (2002), 188-200.
[13] A. Nori and J. Kopeček, Intracellular targeting of polymer-bound drugs for cancer chemotherapy, Advanced Drug Delivery Reviews 57 (2005), 609-636.
[14] S. Poornima, S. Anbu, R. Ravishankaran, S. Sundaramoorthy, K. N. Vennila, A. A. Karande, D. Velmurugan and M. Kandaswamy, DNA and protein targeting 1,2,4-triazole based water soluble dinickel(II) complexes enhances antiproliferation and lactate dehydrogenase inhibition, Polyhedron 62 (2013), 26-36.
[15] P. Singh, R. Raj, V. Kumar, M. P. Mahajan, P. M. S. Bedi, T. Kaur and A. K. Saxena, 1,2,3-Triazole tethered b-lactam-Chalcone bifunctional hybrids: Synthesis and anticancer evaluation, Eur. J. Med. Chem. 47 (2012), 594-600.
[16] A. Petrelli and S. Giordano, From single- to multi-target drugs in cancer therapy: When aspecificity becomes an advantage, Curr. Med. Chem. 15 (2008), 422-432.
[17] M. J. Duffy, The urokinase plasminogen activator system: Role in malignancy, J. Curr. Pharm. Des. 10 (2004), 39-49.
[18] T. Syrovets and T. Simmet, Novel aspects and new roles for the serine protease plasmin, Cell Mol. Life Sci. 61 (2004), 873-885.
[19] M. J. Duffy, Urokinase plasminogen activator and malignancy, Fibrinolysis 7 (1993), 295-302.
[20] P. Mignatti and D. B. Rifkin, Biology and biochemistry of proteinases in tumor invasion, Physiol. Rev. 73 (1993), 161-195.
[21] K. Bdeir, A. Kuo, B. S. Sachais, A. H. Rux, Y. Bdeir, A. Mazar, A. A.-R. Higazi and D. B. Cines, The kringle stabilizes urokinase binding to the urokinase receptor, Blood 102 (2003), 3600-3608.
[22] F. Blasi and P. Carmeliet, uPAR: A versatile signalling orchestrator, Nat. Rev. Mol. Cell Biol. 3 (2002), 932-943.
[23] P. A. Andreasen, L. Kjoller, L. Christensen and M. J. Duffy, The urokinase-type plasminogen activator system in cancer metastasis: A review, Int. J. Cancer 72 (1997), 1-22.
[24] T. Meyer and I. Hart, Mechanisms of tumour metastasis, Eur. J. Cancer 34 (1998), 214-221.
[25] N. Sidenius and F. Blasi, The urokinase plasminogen activator system in cancer: Recent advances and implication for prognosis and therapy, Cancer Metastasis Rev. 22 (2003) 205-222.
[26] M. J. Duffy and C. Duggan, The urokinase plasminogen activator system: A rich source of tumour markers for the individualised management of patients with cancer, Clin Biochem. 37 (2004), 541-548.
[27] E. A. El-Zahany, M. M. Ali, S. A. Drweesh, A. M. A. El-Seidy, B. F. Abdel-Wahab and N. S. Youssef, Synthesis, characterization, and antiproliferative activity of complexes with 3-(2-(4-methoxyphenylcarba-mothioyl)hydrazinyl)-3-OXO-N-(thiazol-2-yl) propanamide against human breast adenocarcinoma cells, Phosphorus, Sulfur, and Silicon and the Related Elements 189 (2014), 762-777.
[28] A. I. Vogel, A Text Book of Quantitative Inorganic Analysis, 4th Edition,
[29] Z. Holzbecher, L. Divis, M. Kral, L. Sucha and F. Vracil, Handbook of Organic Reagents in Inorganic Analysis,
[30] T. M. Salama, A. H. Ahmed and Z. M. El-Bahy, Y-type zeolite-encapsulated copper(II) salicylidene-p-aminobenzoic Schiff base complex: Synthesis, characterization and carbon monoxide adsorption, Microporous and Mesoporous Materials 89 (2006), 251-259.
[31] H.-S. Dong, G.-Y. Huo and Z.-T. Ma, The synthesis of some new (1-aryl-5-methyl-1H-1,2,3-triazol-4-yl) diarylmethanol, Indian J. Chem. 47(B) (2008), 171-174.
[32] P. Skehan, R. Storeng, D. Scudiero, A. Monks, J. Mahon, D. Vistica, J. T. Warren, H. Bokesch, S. Kenney and M. R. Boyd, New colorimetric cytotoxicity assay for anticancer-drug screening, J. Natil. Cancer Inst. 82 (1990), 1107-1112.
[33] L. Li, R. Qu, A. de Kochko, C. Fauquet and R. N. Beachy, An improved rice transformation method using the biolistic method, Plant Cell Rep. 12 (1993), 250-255.
[34] A. Golcu, M. Tumer, H. Demirelli and R. A. Wheatley, Cd(II) and Cu(II) complexes of polydentate Schiff base ligands: Synthesis, characterization, properties and biological activity, Inorg. Chim. Acta 358 (2005), 1785-1797.
[35] M. S. Refat, M. A. A. Moussa and S. F. Mohamed, Synthesis, spectroscopic characterization, thermal analysis and electrical conductivity studies of Mg(II), Ca(II), Sr(II) and Ba(II) vitamin B2 complexes, J. Mol. Str. 994 (2011), 194-201.
[36] S. Ilhan, H. Temel, I. Yilmaz and M. Şekerci, Synthesis and characterization of new macrocyclic Schiff base derived from 2,6-diaminopyridine and 1,7-bis(2-formylphenyl)-1,4,7-trioxaheptane and its Cu(II), Ni(II), Pb(II), Co(III) and La(III) complexes, Polyhedron 26 (2007), 2795-2802.
[37] M. Wang, L.-F. Wang, Y.-Z. Li, Q.-X. Li, Z.-D. Xu and D.-M. Qu, Antitumour activity of transition metal complexes with the thiosemicarbazone derived from 3-acetylumbelliferone, Trans. Met. Chem. 26 (2001), 307-310.
[38] G. Ibrahim,
[39] A. Majumder, G. M. Rosair, A. Mallick, N. Chattopadhyay and S. Mitra, Synthesis, structures and fluorescence of nickel, zinc and cadmium complexes with the N,N,O-tridentate Schiff base N-2-pyridylmethylidene-2-hydroxy-phenylamine, Polyhedron 25 (2006), 1753-1762.
[40] S. Chandra and A. Kumar, Spectral, IR and magnetic studies of Mn(II), Co(II), Ni(II) and Cu(II) complexes with pyrrole-2-carboxyaldehyde thiosemicarbazone (L), Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 68 (2007), 469-473.
[41] G. G. Mohamed, M. M. Omar and A. M. M. Hindy, Synthesis, characterization and biological activity of some transition metals with Schiff base derived from 2-thiophene carboxaldehyde and aminobenzoic acid, Spectrochimica Acta Part A 62 (2005), 1140-1150.
[42] Z. H. A. El-Wahab, Mononuclear metal complexes of organic carboxylic acid derivatives: Synthesis, spectroscopic characterization, thermal investigation and antimicrobial activity, Spectrochimica Acta Part A 67 (2007), 25-38.
[43] A. M. A. El-Seidy, M. M. E. Shakdofa and H. Alshater, Synthesis and characterisation of a porphyrin like Schiff base ligand, its metal complexes and their investigation as antibacterial and antifungal agents, Journal of Applied Sciences Research 9 (2013), 2279-2286.
[44] S. R. Yaul, A. R. Yaul, G. B. Pethe and A. S. Aswar, Synthesis and characterization of transition metal complexes with N,O-Chelating hydrazone Schiff base ligands, Am.-Eura. J. Sci. Res. 4 (2009), 229-234.
[45] M. N. Patel and V. J. Patel, Studies on novel coordination polymers of a tetradentate ligand with some transition metal ions, Synthesis and Reactivity in Inorganic and Metal-Organic Chemistry 19 (1989), 137-155.
[46] S. M. Emam, F. A. El-Saie, S. A. A. El-Enein and H. A. El-Shater, Cobalt(II), nickel(II), copper(II), zinc(II) and hafnium(IV) complexes of N¢-(furan-3-ylmethylene)-2-(4-methoxyphenylamino) acetohydrazide, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 72 (2009), 291-297.
[47] K. Gudasi, M. Patil, R. Vadvai, R. Shenoy and S. Patil, Transition metal complexes with a new tridentate ligand, 5-6-(5-mercapto-1,3,4-oxadiazol-2-yl)pyridin-2-yl-1,3,4-oxadiazole-2-thiol, J. Serb. Chem. Soc. 72 (2007), 357-566.
[48] T. Rosu, M. Negoiu, S. Pasculescu, E. Pahontu, D. Poirier and A. Gulea, Metal-based biologically active agents: Synthesis, characterization, antibacterial and antileukemia activity evaluation of Cu(II), V(IV) and Ni(II) complexes with antipyrine-derived compounds, Eur. J. Med. Chem. 45 (2010), 774-781.
[49] S. Chandra and U. Kumar, Spectral and magnetic studies on manganese(II), cobalt(II) and nickel(II) complexes with Schiff bases, Spectrochimica Acta Part A: Molecular and Biomolecular Spectroscopy 61 (2005), 219-224.
[50] J. T. Makode, A. R. Yaul, S. G. Bhandage and A. S. Aswar, Russ. J. Coord. Chem. 54 (2009), 1372-1377.
[51] V. D. Badwaik, R. D. Deshmukh and A. S. Aswar, Synthesis, structural, and biological studies of some bivalent metal ion complexes with the tridentate Schiff base ligand, Russ. J. Coord. Chem. 35 (2009), 247-252.
[52] E. A. Elzahany, K. H. Hegab, S. K. H. Khalil and N. S. Youssef, Synthesis, characterization and biological activity of some transition metal complexes with Schiff bases derived from 2-formylindole, salicyladehyde, and N-amino rhodanine, Australian Journal of Basic and Applied Sciences 2 (2008), 210-220.
[53] K. Girish Kumar and K. Saji John, Complexation and ion removal studies of a polystyrene anchored Schiff base, Reactive and Functional Polymers 66 (2006), 1427-1433.
[54] N. Raman, S. Ravichandran and C. Thangaraja, Copper(II), cobalt(II), nickel(II) and zinc(II) complexes of Schiff base derived from benzil-2,4-dinitrophenylhydrazone with aniline, J. Chem. Sci. 116 (2004), 215-219.
[55] M. Tümer, D. Ekinci, F. Tumer and A. Bulut, Synthesis, characterization and properties of some divalent metal(II) complexes: Their electrochemical, catalytic, thermal and antimicrobial activity studies, Spectrochim. Acta Part A: Mol. Biomol. Spectrosc. 67 (2007), 916-929.